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Sun-Jin Kim Selected Research

AEE 788 (AEE788)

1/2008Targeting the EGFR, VEGFR, and PDGFR on colon cancer cells and stromal cells is required for therapy.
12/2007Inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation on tumor-associated endothelial cells leads to treatment of orthotopic human colon cancer in nude mice.
12/2006Therapy of multidrug resistant human prostate tumors in the prostate of nude mice by simultaneous targeting of the epidermal growth factor receptor and vascular endothelial growth factor receptor on tumor-associated endothelial cells.
7/2005Induction of apoptosis in tumor-associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice.
7/2005Antivascular therapy for orthotopic human ovarian carcinoma through blockade of the vascular endothelial growth factor and epidermal growth factor receptors.
6/2005Antivascular therapy of human follicular thyroid cancer experimental bone metastasis by blockade of epidermal growth factor receptor and vascular growth factor receptor phosphorylation.
5/2005Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model.

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Sun-Jin Kim Research Topics

Disease

35Neoplasms (Cancer)
04/2016 - 08/2002
18Neoplasm Metastasis (Metastasis)
04/2016 - 08/2002
13Prostatic Neoplasms (Prostate Cancer)
12/2017 - 08/2002
9Lymphatic Metastasis
07/2011 - 08/2002
6Brain Neoplasms (Brain Tumor)
04/2016 - 08/2010
5Breast Neoplasms (Breast Cancer)
04/2016 - 08/2010
5Pancreatic Neoplasms (Pancreatic Cancer)
04/2015 - 07/2005
5Colonic Neoplasms (Colon Cancer)
05/2008 - 05/2005
4Lung Neoplasms (Lung Cancer)
04/2016 - 08/2010
4Carcinoma (Carcinomatosis)
02/2012 - 05/2005
2Ovarian Neoplasms (Ovarian Cancer)
02/2012 - 02/2011
2Melanoma (Melanoma, Malignant)
09/2010 - 08/2010
1Carcinogenesis
12/2017
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2016
1Glioma (Gliomas)
10/2015
1Glioblastoma (Glioblastoma Multiforme)
10/2015
1Acute Tubulointerstitial Nephritis
08/2012
1Human Influenza (Influenza)
01/2012
1Obesity
11/2011
1Chronic Pancreatitis
04/2011
1Ascites
02/2011
1Wounds and Injuries (Trauma)
05/2009
1Necrosis
05/2008

Drug/Important Bio-Agent (IBA)

12Paclitaxel (Taxol)FDA LinkGeneric
04/2016 - 08/2002
10ErbB Receptors (EGF Receptor)IBA
05/2008 - 03/2003
8Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
10/2008 - 08/2002
7Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
10/2008 - 08/2004
7AEE 788 (AEE788)IBA
01/2008 - 05/2005
6Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2008 - 08/2002
6Imatinib Mesylate (Gleevec)FDA Link
01/2008 - 06/2004
5Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
05/2008 - 05/2005
5Epidermal Growth Factor (EGF)IBA
02/2008 - 03/2003
4Proteins (Proteins, Gene)FDA Link
04/2016 - 04/2011
4Endothelin Receptors (Endothelin Receptor)IBA
04/2016 - 02/2011
4Endothelins (Endothelin)IBA
04/2016 - 02/2012
4macitentanIBA
04/2016 - 02/2011
4Endothelin Receptor AntagonistsIBA
10/2015 - 02/2011
4Irinotecan (Camptosar)FDA LinkGeneric
05/2008 - 05/2005
4Tyrosine Kinase InhibitorsIBA
05/2008 - 03/2003
3Small Interfering RNA (siRNA)IBA
07/2011 - 05/2008
3Transforming Growth Factor alpha (TGF-alpha)IBA
05/2008 - 05/2005
3AndrogensIBA
05/2008 - 03/2003
3Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
02/2008 - 08/2002
3Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2008 - 02/2003
3Docetaxel (Taxotere)FDA Link
10/2007 - 10/2002
2Biomarkers (Surrogate Marker)IBA
12/2017 - 04/2011
2Bovine Serum AlbuminIBA
05/2015 - 10/2008
2GemcitabineFDA Link
04/2015 - 07/2005
2Pharmaceutical PreparationsIBA
04/2015 - 05/2005
2Mitogen-Activated Protein KinasesIBA
12/2014 - 06/2005
2Peptides (Polypeptides)IBA
12/2014 - 02/2003
2Interleukin-6 (Interleukin 6)IBA
12/2014 - 07/2011
2Biological ProductsIBA
03/2011 - 01/2008
2Green Fluorescent ProteinsIBA
12/2010 - 05/2009
2PKI 166IBA
05/2008 - 03/2003
2Proliferating Cell Nuclear Antigen (PCNA)IBA
05/2008 - 08/2002
2human ERBB2 proteinIBA
05/2008 - 12/2007
2Phosphotransferases (Kinase)IBA
05/2008 - 06/2006
2Growth Factor ReceptorsIBA
02/2008 - 06/2005
2Matrix Metalloproteinases (MMPs)IBA
11/2007 - 08/2002
2Therapeutic UsesIBA
05/2005 - 03/2003
1Androgen Receptors (Androgen Receptor)IBA
12/2017
1Temozolomide (Temodar)FDA LinkGeneric
10/2015
1Culture MediaIBA
05/2015
1oleandrinIBA
04/2015
1Cardiac GlycosidesIBA
04/2015
1PBI-05204IBA
04/2015
1Branched-Chain Amino AcidsIBA
02/2015
1Glucose (Dextrose)FDA LinkGeneric
02/2015
1Glutamine (L-Glutamine)FDA Link
02/2015
1GlycogenIBA
02/2015
1PentosesIBA
02/2015
1purineIBA
02/2015
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
12/2014
1Interleukin-8 (Interleukin 8)IBA
12/2014
1NitrogenIBA
08/2012
1CreatinineIBA
08/2012
1TinIBA
08/2012
1Urea (Carbamide)FDA LinkGeneric
08/2012
1LK8 peptideIBA
08/2012
1Hemagglutinins (Hemagglutinin)IBA
01/2012
1SolventsIBA
11/2011
1Liposomes (Liposome)IBA
07/2011
1Clodronic Acid (Clodronate)IBA
07/2011
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2011
1LipopolysaccharidesIBA
12/2010
1Nitric Oxide (Nitrogen Monoxide)FDA Link
12/2010
1InterferonsIBA
12/2010
1CalciumIBA
09/2010
1Neuroprotective AgentsIBA
09/2010
1DesminIBA
05/2009
1AcidsIBA
10/2008
1Biotin (Vitamin H)FDA Link
10/2008
1diethylenetriamineIBA
10/2008
1Dasatinib (BMS 354825)FDA Link
05/2008

Therapy/Procedure

23Therapeutics
04/2016 - 08/2002
7Drug Therapy (Chemotherapy)
04/2016 - 05/2005
3Oral Administration
07/2005 - 03/2003
2Castration
12/2017 - 10/2007
1Intravenous Infusions
08/2012